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Distribution of Ventilation/Perfusion Ratios in Pulmonary intercalation: An accoutrement to the Interpretation of Ventilation/Perfusion Lung Scans Emmanuel Itti, MD; Severine Nguyen, MD; Fabrice Robin, MD; Serge Desarnaud, MD; Jean Rosso, MD; ´ Alain Harf, MD, PhD; and Michel Meignan, MD, PhD Department of Nuclear Medicine, Henri Mondor Hospital, Paris 12 University, Creteil, France ´ Diagnosis of pulmonary embolism (PE) by visual translation of ventilation/perfusion (V/Q) scans is limited by the high percentages of patients classi?ed in the intermediate- and confused- hazard categories. This study proposes a quantitative synopsis of the dissemination of V/Q ratios to better identify patients with PE. Methods: We studied 99 straight patients who underwent dual-isotope 81mKr/99mTc-macroaggregate V/Q scanning and arterial blood gas analysis at heart 48 h. The 8-view V/Q scans were visually study by 2 observers according to the revised criteria of the Prospective inves tigation of Pulmonary Embolism Diagnosis (PIOPED) (normal scan or low, intermediate, or high probability of PE). Quantitative analysis of the posterior-view distribution histogram of V/Q ratios was performed using commit software.

Brie?y, regions of interest were drawn around the lungs on the matched V/Q images, sedate ?ltering was applied, normalized regional V/Q ratios were calculated inwardly each pixel, and a distribution histogram was built. Results: Patients with normal scans (n 16) had a predominance of V/Q ratios (63.3% 13.0%) amongst 0.8 and 1.2. They had only 9.8% 5.8% of ratios 1.2, and the remaining 26.9% 7.5% of ratios were 0.8. By contrast, patients with PE (n 34) w! ere characterized by a signi? argot increase (15.5 10.0%, P 0.04) in high V/Q ratios ( 1.2) and a signi?cant increase (34.5% 8.2%, P 0.003) in low V/Q ratios ( 0.8). Interestingly, a similar pattern was found in patients with a high PIOPED probability of PE, 21.3% 11.0% and 37.5% 9.2%, respectively. Within the nondiagnostic group...If you want to channel a full essay, order it on our website: BestEssayCheap.com

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